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[Peculiarities of lipid disorders in patients with type II diabetes mellitus: in which cases we should administer statins?].

Authors :
Mamedov MN
Source :
Kardiologiia [Kardiologiia] 2006; Vol. 46 (3), pp. 90-6.
Publication Year :
2006

Abstract

Cardiovascular complications are a principal cause of death rate in the patients with type 2 diabetes, that in turn contribute to cardiovascular diseases and complications in adult population. According to UKPDS data high LDL Ch level is strong predictor of CHD development in patients with type 2 diabetes and its 1 mmol/l level increase, due the coronary risk increase on 57%. Patients with type 2 diabetes have the target levels of lipids enough rigid: the total Ch < 4.5 mmol/l, LDL Ch < 2.5 mmol/l, triglycerides < 1.7 mmol/l and HDL Ch > 1 mmol/l. The results of CARDS study have shown, that the treatment of the type 2 diabetes patients with mild hypercholesterolemia without CHD by atorvastatin in a doze of 10 mg during 5 years decreased cardiovascular risk on 37%, an stroke on 48% and the total death rate on 27%. In practice, 89% of the patients with type 2 diabetes comes to light deviations in Ch level. The lipid spectrum assay of should join to the obligatory diagnostic procedures in all type 2 diabetes patients despite of the age and sex. Statin therapy in the diabetes patients is as necessary as the antidiabetic treatment.

Details

Language :
Russian
ISSN :
0022-9040
Volume :
46
Issue :
3
Database :
MEDLINE
Journal :
Kardiologiia
Accession number :
16710267