Is it time to abandon microsatellite instability as a pre-screen for selecting families for mutation testing for mismatch repair genes?

Subjects

Subjects :

Base Pair Mismatch
Cost-Benefit Analysis
DNA Mutational Analysis economics
Germ-Line Mutation
Humans
Immunohistochemistry
Neoplasms etiology
Neoplasms genetics
Pedigree
Risk Factors
Chromosomal Instability
DNA Repair genetics
Genetic Testing
Microsatellite Repeats

Details

Language :

English

ISSN :

1527-7755

Volume :

24

Issue :

12

Database :

MEDLINE

Journal :

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Publication Type :

Editorial & Opinion

Accession number :

16622277

Full Text :

https://doi.org/10.1200/JCO.2005.05.3207