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Multifactorial approach and adherence to prescribed oral medications in patients with type 2 diabetes.

Authors :
Mateo JF
Gil-Guillén VF
Mateo E
Orozco D
Carbayo JA
Merino J
Source :
International journal of clinical practice [Int J Clin Pract] 2006 Apr; Vol. 60 (4), pp. 422-8.
Publication Year :
2006

Abstract

The aims of this study were to assess adherence to oral hypoglycaemic/cardiovascular drugs and determine non-adherence predictors in type 2 diabetes patients. It was designed as a population-based cross-sectional study in which 90 patients from a primary care setting were studied. Pill count and self-report methods were used to measure adherence. Logistic regression analysis was performed to predict factors related to non-adherence. Adequate adherence to all drugs was found in 29 patients (35.4%; 95% confidence interval (CI) 25.0-45.7). Variables associated with non-adherence were HbA1c odds ratio (OR) 2.32 (95% CI: 1.09-4.95), systolic blood pressure OR 1.68 (95% CI: 1.08-2.62), total cholesterol OR 1.34 (95% CI: 1.08-1.66), number of pills OR 1.80 (95% CI: 1.26-2.55) and duration of disease OR 0.44 (CI 95%: 0.24-0.83). In conclusion, one in three patients had adequate adherence. Factors associated with non-adherence were duration of disease, complexity of drug regimen and inadequate control of cardiovascular risk factors.

Details

Language :
English
ISSN :
1368-5031
Volume :
60
Issue :
4
Database :
MEDLINE
Journal :
International journal of clinical practice
Publication Type :
Academic Journal
Accession number :
16620354
Full Text :
https://doi.org/10.1111/j.1368-5031.2006.00799.x