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[UV spectrophotometric assay of famotidine in combination with picrolonic acid, picrolinate].
- Source :
-
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi [Rev Med Chir Soc Med Nat Iasi] 2005 Apr-Jun; Vol. 109 (2), pp. 422-5. - Publication Year :
- 2005
-
Abstract
- Famotidine, belonging to H2-antagonist group, is a compound containing a thiazolic moiety and it is used in peptic ulcer therapy. This paper debates the possibility of developing a new ultraviolet spectrophotometric assessment by using the reaction between famotidine and picrolonic acid. We carried out our determinations at 362 nm, where the absorbency of famotidine - picrolonic acid complex is maximal, and we have established the optimal reaction conditions. This method was successfully applied for famotidine assay from pharmaceutical dosage forms.
- Subjects :
- Anti-Ulcer Agents analysis
Famotidine therapeutic use
Histamine H2 Antagonists therapeutic use
Humans
Indicators and Reagents
Peptic Ulcer drug therapy
Pharmaceutical Solutions analysis
Pyrazolones therapeutic use
Famotidine analysis
Histamine H2 Antagonists analysis
Pyrazolones analysis
Spectrophotometry, Ultraviolet methods
Subjects
Details
- Language :
- Romanian; Moldavian; Moldovan
- ISSN :
- 0048-7848
- Volume :
- 109
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi
- Publication Type :
- Academic Journal
- Accession number :
- 16607813