Back to Search
Start Over
[With genechip technique to investigate HLA-DQB1 gene polymorphisms in south and north regions of China].
- Source :
-
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics [Zhonghua Yi Xue Yi Chuan Xue Za Zhi] 2006 Apr; Vol. 23 (2), pp. 238-9. - Publication Year :
- 2006
-
Abstract
- Objective: To research and compare HLA-DQB1 gene frequency(GF) and polymorphism distribution between south and north population of Chinese in China.<br />Methods: Combining PCR-sequence specific primers(SSP) and sequence specific oligonucleotide probe(SSOP) techniques and DNA Microarray Kit for HLA-DQB1 Low Res Genotyping from Shenzhen Yi-Shengtang Biological LTD. Co. was used to type HLA-DQB1 gene polymorphisms of 700 individuals living in south China and 320 individuals in north China.<br />Results: We inspected 10 alleles of HLA-DQB1 and got a series of comprehensive and accurate statistic data.<br />Conclusion: It is tested that HLA-DQB1*02, 05, 0601, 0602, 0603 gene frequencies are different obviously(P<0.05) between south and north Chinese. And those data will be useful to kinds of research associated with disease relevant and anthropology research.
Details
- Language :
- Chinese
- ISSN :
- 1003-9406
- Volume :
- 23
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics
- Publication Type :
- Academic Journal
- Accession number :
- 16604509