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Potential role of Clostridium difficile as a cause of duodenitis-proximal jejunitis in horses.
- Source :
-
Journal of medical microbiology [J Med Microbiol] 2006 May; Vol. 55 (Pt 5), pp. 605-608. - Publication Year :
- 2006
-
Abstract
- Duodenitis-proximal jejunitis (DPJ) is an idiopathic condition in the horse characterized by inflammation and oedema of the duodenum and proximal jejunum. Clinical signs include colic, ileus, depression, fluid accumulation in the small intestine and stomach, and endotoxaemia. The objective of this study was to investigate prospectively the role of Clostridium difficile in this idiopathic disease. Nasogastric reflux from 10 consecutive cases with DPJ and 16 consecutive horses with other causes of nasogastric reflux was cultured for C. difficile, other Clostridium spp., and Salmonella. Toxigenic strains of C. difficile were isolated from 10/10 (100%) of horses with DPJ and 1/16 controls (P<0.0001). No other known pathogenic clostridia were isolated from either group. Results of this study suggest that C. difficile might be an important cause of this syndrome.
- Subjects :
- Animals
Clostridioides difficile pathogenicity
Clostridium Infections microbiology
Duodenitis microbiology
Gastroesophageal Reflux microbiology
Horses
Jejunal Diseases microbiology
Salmonella isolation & purification
Clostridioides difficile isolation & purification
Clostridium Infections veterinary
Duodenitis veterinary
Horse Diseases microbiology
Jejunal Diseases veterinary
Subjects
Details
- Language :
- English
- ISSN :
- 0022-2615
- Volume :
- 55
- Issue :
- Pt 5
- Database :
- MEDLINE
- Journal :
- Journal of medical microbiology
- Publication Type :
- Academic Journal
- Accession number :
- 16585649
- Full Text :
- https://doi.org/10.1099/jmm.0.46334-0