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Tissue integration of the collagen-hydroxylapatite implant: histological examination in canine bone and surrounding tissues.
- Source :
-
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery [Eur Arch Otorhinolaryngol] 1991; Vol. 248 (6), pp. 337-41. - Publication Year :
- 1991
-
Abstract
- Using the dog as an animal model, we have tested an implant material composed of purified fibrillar collagen (PFC) and particulate hydroxylapatite (HA) in the mandible and in surrounding tissues. Bone and tissue samples were taken at 2, 4 and 6 months for histological study. After 2 months, the PFC was replaced by fibro-connective host tissues. After 4 months, some small areas of ossification were observed around the HA particles. After 6 months, the fibro-connective tissue was replaced by neo-formed bone in the mandible. PFC was found to increase the interfaces between the HA particles and the host tissues, permitting HA integration into the bone. The PFC/HA implant was also molded when moistened by blood or saline solution and then became mis-sharpen by local pressures exerted. These findings show that the implant should preferably be reserved for the restoration of bones not subjected to significant forces or local stresses.
- Subjects :
- Animals
Connective Tissue pathology
Dogs
Durapatite
Facial Muscles pathology
Facial Muscles surgery
Fascia pathology
Fasciotomy
Macrophages pathology
Mandible surgery
Materials Testing
Surface Properties
Time Factors
Collagen chemistry
Hydroxyapatites chemistry
Mandible pathology
Osseointegration
Prostheses and Implants
Subjects
Details
- Language :
- English
- ISSN :
- 0937-4477
- Volume :
- 248
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
- Publication Type :
- Academic Journal
- Accession number :
- 1657049
- Full Text :
- https://doi.org/10.1007/BF00169025