Keeping p53 in check: essential and synergistic functions of Mdm2 and Mdm4.

Subjects

Subjects :

Animals
Antineoplastic Agents pharmacology
Apoptosis
Cell Differentiation
Cell Proliferation
Humans
Mice
Mice, Knockout
Neurons cytology
Neurons metabolism
Phenotype
Promoter Regions, Genetic genetics
Proto-Oncogene Proteins antagonists & inhibitors
Proto-Oncogene Proteins genetics
Proto-Oncogene Proteins c-mdm2 antagonists & inhibitors
Proto-Oncogene Proteins c-mdm2 genetics
Stem Cells cytology
Stem Cells metabolism
Transcriptional Activation
Tumor Suppressor Protein p53 genetics
Ubiquitin metabolism
Ubiquitin-Protein Ligases antagonists & inhibitors
Ubiquitin-Protein Ligases genetics
Gene Expression Regulation, Developmental
Protein Processing, Post-Translational
Proto-Oncogene Proteins metabolism
Proto-Oncogene Proteins c-mdm2 metabolism
Tumor Suppressor Protein p53 metabolism
Ubiquitin-Protein Ligases metabolism

Details

Language :

English

ISSN :

1350-9047

Volume :

13

Issue :

6

Database :

MEDLINE

Journal :

Cell death and differentiation

Publication Type :

Academic Journal

Accession number :

16543935

Full Text :

https://doi.org/10.1038/sj.cdd.4401912