Back to Search
Start Over
Disseminated Kikuchi-Fujimoto disease: a case report.
- Source :
-
Joint bone spine [Joint Bone Spine] 2006 May; Vol. 73 (3), pp. 311-3. Date of Electronic Publication: 2006 Jan 04. - Publication Year :
- 2006
-
Abstract
- Subacute necrotizing lymphadenitis or Kikuchi-Fujimoto disease is a benign pathological entity diagnosed chiefly in young adults. We report a case in a 20-year-old woman who presented with swollen lymph nodes and a fever. Disseminated lymphadenopathy with nodes measuring up to 6 cm in diameter was found upon physical examination. The erythrocyte sedimentation rate was elevated to 40 mm/h and the lactic dehydrogenase level to 593 IU/l. Findings were negative from serological tests for rubella, hepatitis B, hepatitis C, HIV, and toxoplasmosis, as well as from tests for tuberculosis. A biopsy of a cervical lymph node showed nonsuppurative necrosis, karyorrhexis, and a marked histiocytic reaction consistent with Kikuchi-Fujimoto disease. No treatment was given, and a full recovery was achieved within 3 months. In this patient, the disseminated lymphadenopathy and constitutional symptoms strongly suggested a hematological malignancy and more specifically a lymphoproliferative disease.
Details
- Language :
- English
- ISSN :
- 1297-319X
- Volume :
- 73
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Joint bone spine
- Publication Type :
- Academic Journal
- Accession number :
- 16495107
- Full Text :
- https://doi.org/10.1016/j.jbspin.2004.12.015