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[Clinical analysis of 1,142 hospitalized cantonese patients with nasopharyngeal carcinoma].
- Source :
-
Ai zheng = Aizheng = Chinese journal of cancer [Ai Zheng] 2006 Feb; Vol. 25 (2), pp. 204-8. - Publication Year :
- 2006
-
Abstract
- Background & Objective: Few large-scale epidemiologic investigations of nasopharyngeal carcinoma (NPC) at high incidence region in Guangdong province were reported in recent 20 years. This study was to summarize clinical data of a population of hospitalized Cantonese NPC patients,analyze the epidemiologic characteristics of NPC in the high incidence region, and provide references for the prevention and treatment of NPC.<br />Methods: Clinical data of 1 142 Cantonese NPC patients, hospitalized in Cancer Center of Sun Yat-sen University between Jan. 1998 and Aug. 2000, were collected according to well-designed forms and statistically analyzed.<br />Results: The morbidity of NPC in Cantonese showed obvious family clustering: 21.9% of the patients had family history of cancer, and 12.3% had family history of NPC. Moreover, the family clustering feature was more obvious in the population from the region with higher incidence of NPC. The positive rate of VCA/IgA antibody was 90.0%, and that of EA/IgA antibody was 74.5%; the titers were positively related to tumor burden. Early diagnostic rate of NPC was about 30%.<br />Conclusions: NPC patients in Cantonese population have obvious family and territorial clustering. High positive rates of VCA/IgA and EA/IgA antibodies are helpful for early diagnosis of NPC.
- Subjects :
- Adolescent
Adult
Aged
Aged, 80 and over
Antigens, Viral immunology
Capsid Proteins immunology
Child
China epidemiology
Female
Humans
Immunoglobulin A analysis
Male
Middle Aged
Morbidity
Neoplasm Staging
Carcinoma, Squamous Cell epidemiology
Carcinoma, Squamous Cell genetics
Carcinoma, Squamous Cell immunology
Carcinoma, Squamous Cell pathology
Genetic Predisposition to Disease
Nasopharyngeal Neoplasms epidemiology
Nasopharyngeal Neoplasms genetics
Nasopharyngeal Neoplasms immunology
Nasopharyngeal Neoplasms pathology
Subjects
Details
- Language :
- Chinese
- Volume :
- 25
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Ai zheng = Aizheng = Chinese journal of cancer
- Publication Type :
- Academic Journal
- Accession number :
- 16480587