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Rotaxanes of cyclic peptides.

Authors :
Aucagne V
Leigh DA
Lock JS
Thomson AR
Source :
Journal of the American Chemical Society [J Am Chem Soc] 2006 Feb 15; Vol. 128 (6), pp. 1784-5.
Publication Year :
2006

Abstract

The synthesis of rotaxanes derived from the synthetic peptide macrocycles cyclo(l-ProGly)4 and cyclo(l-ProGly)5 and diammonium threads is described. [2]Rotaxanes are formed in good yields (56-63%), despite the disruption of internal amide-amide hydrogen bonding in the macrocycles.

Details

Language :
English
ISSN :
0002-7863
Volume :
128
Issue :
6
Database :
MEDLINE
Journal :
Journal of the American Chemical Society
Publication Type :
Academic Journal
Accession number :
16464065
Full Text :
https://doi.org/10.1021/ja057206q