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Recent advances in combinatorial chemistry applied to development of anti-HIV drugs.
- Source :
-
Mini reviews in medicinal chemistry [Mini Rev Med Chem] 2006 Jan; Vol. 6 (1), pp. 91-108. - Publication Year :
- 2006
-
Abstract
- A compilation of combinatorial chemistry techniques applied to anti-HIV drug development is presented in this review. This synthetic strategy together with high throughput screening assays has allowed the discovery and optimization of novel lead anti-HIV compounds.
- Subjects :
- Anti-HIV Agents chemistry
Anti-HIV Agents pharmacology
HIV drug effects
HIV physiology
HIV Fusion Inhibitors chemical synthesis
HIV Integrase Inhibitors chemical synthesis
HIV Protease Inhibitors chemical synthesis
Humans
Molecular Structure
Reverse Transcriptase Inhibitors chemical synthesis
Anti-HIV Agents chemical synthesis
Combinatorial Chemistry Techniques methods
Subjects
Details
- Language :
- English
- ISSN :
- 1389-5575
- Volume :
- 6
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Mini reviews in medicinal chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 16457634
- Full Text :
- https://doi.org/10.2174/138955706775197820