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10. Atopic dermatitis.
- Source :
-
The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2006 Feb; Vol. 117 (2 Suppl Mini-Primer), pp. S475-80. - Publication Year :
- 2006
-
Abstract
- Atopic dermatitis is a common chronic inflammatory skin disease often preceding the development of asthma and allergic disorders, such as food allergy or allergic rhinoconjunctivitis. Pathophysiology involves a complex series of interactions between resident and infiltrating cells orchestrated by proinflammatory cytokines and chemokines. A deficiency of antimicrobial peptides might contribute to the propensity for colonization or infection by microbial organisms seen in atopic dermatitis. New treatment approaches include use of topical steroids as maintenance therapy and use of topical calcineurin inhibitors for early intervention with topical steroids used as rescue therapy.
- Subjects :
- Administration, Topical
Anti-Infective Agents metabolism
Calcineurin administration & dosage
Calcineurin therapeutic use
Calcineurin Inhibitors
Cytokines physiology
Dermatitis, Atopic diagnosis
Diagnosis, Differential
Humans
Patch Tests
Skin immunology
Skin metabolism
Steroids administration & dosage
Steroids therapeutic use
Dermatitis, Atopic physiopathology
Dermatitis, Atopic therapy
Subjects
Details
- Language :
- English
- ISSN :
- 0091-6749
- Volume :
- 117
- Issue :
- 2 Suppl Mini-Primer
- Database :
- MEDLINE
- Journal :
- The Journal of allergy and clinical immunology
- Publication Type :
- Academic Journal
- Accession number :
- 16455350
- Full Text :
- https://doi.org/10.1016/j.jaci.2005.10.018