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10. Atopic dermatitis.

Authors :
Boguniewicz M
Leung DY
Source :
The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2006 Feb; Vol. 117 (2 Suppl Mini-Primer), pp. S475-80.
Publication Year :
2006

Abstract

Atopic dermatitis is a common chronic inflammatory skin disease often preceding the development of asthma and allergic disorders, such as food allergy or allergic rhinoconjunctivitis. Pathophysiology involves a complex series of interactions between resident and infiltrating cells orchestrated by proinflammatory cytokines and chemokines. A deficiency of antimicrobial peptides might contribute to the propensity for colonization or infection by microbial organisms seen in atopic dermatitis. New treatment approaches include use of topical steroids as maintenance therapy and use of topical calcineurin inhibitors for early intervention with topical steroids used as rescue therapy.

Details

Language :
English
ISSN :
0091-6749
Volume :
117
Issue :
2 Suppl Mini-Primer
Database :
MEDLINE
Journal :
The Journal of allergy and clinical immunology
Publication Type :
Academic Journal
Accession number :
16455350
Full Text :
https://doi.org/10.1016/j.jaci.2005.10.018