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Clinical and virological associations between external anogenital warts and cervical HPV infection in an STD clinic population.

Authors :
Law CL
Merianos A
Grace J
Rose BR
Thompson CH
Cossart YE
Source :
International journal of STD & AIDS [Int J STD AIDS] 1991 Jan-Feb; Vol. 2 (1), pp. 30-6.
Publication Year :
1991

Abstract

To determine the significance of overt anogenital warts as indicators of human papillomavirus (HPV) infection of the cervix, 177 women attending a Sydney STD clinic were screened for evidence of cervical HPV infection using clinical criteria together with cytology and HPV DNA dot hybridization. HPV DNA probing was also performed on biopsies of 50 exophytic warts. A very high prevalence of both anogenital warts (40%), and of cervical HPV infection (58%) was indicated in this group of women. In the exophytic warts, HPV types 6/11 were most commonly detected, whereas the rates of detection of types 6/11 and 16/18 in the cervix were similar. Of the 87 women with evidence of cervical HPV infection, 57 (66%) had a history of either past or current overt exophytic anogenital warts; while the corresponding figure for the 90 women with no evidence of cervical infection was 45 (50%). Cytological evidence of dysplasia (CIN I-III) was detected in 13 (7%) of the cervical smears: of these, 4 were positive for HPV 16/18 only, 2 for 6/11 only and 4 for both 6/11 and 16/18.

Details

Language :
English
ISSN :
0956-4624
Volume :
2
Issue :
1
Database :
MEDLINE
Journal :
International journal of STD & AIDS
Publication Type :
Academic Journal
Accession number :
1645205
Full Text :
https://doi.org/10.1177/095646249100200106