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PNA-based reagents for the direct and site-specific synthesis of thymine dimer lesions in genomic DNA.

Authors :
Pieck JC
Kuch D
Grolle F
Linne U
Haas C
Carell T
Source :
Journal of the American Chemical Society [J Am Chem Soc] 2006 Feb 08; Vol. 128 (5), pp. 1404-5.
Publication Year :
2006

Abstract

An acetophenone containing PNA-based reagent was designed for the direct and site-specific synthesis of a cis-syn thymidine dimer lesion in genomic DNA.

Details

Language :
English
ISSN :
0002-7863
Volume :
128
Issue :
5
Database :
MEDLINE
Journal :
Journal of the American Chemical Society
Publication Type :
Academic Journal
Accession number :
16448083
Full Text :
https://doi.org/10.1021/ja056358i