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PNA-based reagents for the direct and site-specific synthesis of thymine dimer lesions in genomic DNA.
- Source :
-
Journal of the American Chemical Society [J Am Chem Soc] 2006 Feb 08; Vol. 128 (5), pp. 1404-5. - Publication Year :
- 2006
-
Abstract
- An acetophenone containing PNA-based reagent was designed for the direct and site-specific synthesis of a cis-syn thymidine dimer lesion in genomic DNA.
- Subjects :
- Acetophenones chemical synthesis
Bacteriophages genetics
Base Sequence
DNA chemistry
DNA genetics
Deoxyribonucleases, Type II Site-Specific chemistry
Horseradish Peroxidase chemistry
Molecular Sequence Data
Streptavidin chemistry
Substrate Specificity
Acetophenones chemistry
DNA chemical synthesis
Peptide Nucleic Acids chemistry
Pyrimidine Dimers chemical synthesis
Subjects
Details
- Language :
- English
- ISSN :
- 0002-7863
- Volume :
- 128
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Journal of the American Chemical Society
- Publication Type :
- Academic Journal
- Accession number :
- 16448083
- Full Text :
- https://doi.org/10.1021/ja056358i