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Wnt signalling in lung development and diseases.

Authors :
Pongracz JE
Stockley RA
Source :
Respiratory research [Respir Res] 2006 Jan 26; Vol. 7, pp. 15. Date of Electronic Publication: 2006 Jan 26.
Publication Year :
2006

Abstract

There are several signalling pathways involved in lung organogenesis including Notch, TGFbeta/BMP, Sonic hedgehog (Shh), FGF, EGF, and Wnt. Despite the widely acknowledged significance of Wnt signalling in embryonic lung development, the role of different Wnt pathways in lung pathologies has been slow to emerge. In this review, we will present a synopsis of current Wnt research with particular attention paid to the role of Wnt signals in lung development and in pulmonary diseases.

Details

Language :
English
ISSN :
1465-993X
Volume :
7
Database :
MEDLINE
Journal :
Respiratory research
Publication Type :
Academic Journal
Accession number :
16438732
Full Text :
https://doi.org/10.1186/1465-9921-7-15