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[Evaluation of the antimicrobial potential of immune sera].

Authors :
Mikhaĭlova NA
Bitkova EE
Skala LZ
Khvatov VB
Krivoshein IuS
Source :
Zhurnal mikrobiologii, epidemiologii i immunobiologii [Zh Mikrobiol Epidemiol Immunobiol] 2005 Nov-Dec (6), pp. 34-8.
Publication Year :
2005

Abstract

The inhibiting activity of blood sera obtained from 20 volunteers immunized with the multi-component vaccine "PYOPOL", 25 nonimmune donors and 7 lots of human antistaphylococcal immunoglobulin with respect to Staphylococcus aureus, Escherichia coli, Proteus vulgaris and Pseudomonas aeruginosa has been studied in the liquid nutrient medium with the use an automated microbiological analyzer. The sera of donors immunized with the vaccine "PYOPOL" have been found to possess high antimicrobial activity, comparable with the definite concentration of the antiseptic agent "Myramistin". The proposed method may be recommended for the evaluation of the bacteriostatic activity of different immuno- biological preparations.

Details

Language :
Russian
ISSN :
0372-9311
Issue :
6
Database :
MEDLINE
Journal :
Zhurnal mikrobiologii, epidemiologii i immunobiologii
Publication Type :
Academic Journal
Accession number :
16438372