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[Frequency of different infectious agents persistence in mononuclear leukocytes of blood and synovial fluid in patients with rheumatoid arthritis].
- Source :
-
Likars'ka sprava [Lik Sprava] 2005 Jul-Sep (5-6), pp. 28-32. - Publication Year :
- 2005
-
Abstract
- The study of persistence in mononuclear leukocytes (ML) of blood and synovial fluid of 218 patients with rheumatoid arthritis (RA) Cytornegalovirus (CMV), the 1-st and 2-nd types of Herpes virus simplex (VH), Epstain-Barr virus (VEB), Mycoplasma arthritidis (Ma), Mycoplasma fermentans (Mf), Ureaplasma urealiticum (U), Chlamidia trachomatis (Ct), viruses of Hepatitis B and C was carry out by direct and indirect immunofruorescence, immunoenzymatic analysis and polymerase chain reaction. An increased frequency of contamination of blood ML with infectious agents in patients with RA was established (57,4% compared with 16,7% in control group). The following infectious agents were revieled more frequently: in ML of blood and synovial fluid the Ma (relatively 20,5% and 15,9%), Mf (15,6% and 13,2%), Ct (18,4% and 13,2%), VH (27,1% and 10,5%), VEB (12,7% and 5,3%) and CMV (11,2% and 7,9%). Types of frequency dynamics of ML contamination with these infectious agents in different time phases of RA were determined.
- Subjects :
- Antibodies, Bacterial analysis
Antigens, Bacterial analysis
Antigens, Viral analysis
Chlamydia trachomatis immunology
Chlamydia trachomatis isolation & purification
Cytomegalovirus immunology
Cytomegalovirus isolation & purification
DNA, Bacterial analysis
DNA, Viral analysis
Female
Fluorescent Antibody Technique, Indirect
Hepacivirus immunology
Hepacivirus isolation & purification
Hepatitis B virus immunology
Hepatitis B virus isolation & purification
Herpes Simplex classification
Herpes Simplex immunology
Herpesvirus 4, Human immunology
Herpesvirus 4, Human isolation & purification
Humans
Infections complications
Infections virology
Leukocytes, Mononuclear immunology
Leukocytes, Mononuclear virology
Male
Mycoplasma arthritidis immunology
Mycoplasma arthritidis isolation & purification
Mycoplasma fermentans immunology
Mycoplasma fermentans isolation & purification
Polymerase Chain Reaction
RNA, Viral analysis
Retrospective Studies
Synovial Fluid immunology
Synovial Fluid virology
Ukraine epidemiology
Ureaplasma urealyticum immunology
Ureaplasma urealyticum isolation & purification
Arthritis, Rheumatoid blood
Infections microbiology
Leukocytes, Mononuclear microbiology
Synovial Fluid microbiology
Subjects
Details
- Language :
- Ukrainian
- ISSN :
- 1019-5297
- Issue :
- 5-6
- Database :
- MEDLINE
- Journal :
- Likars'ka sprava
- Publication Type :
- Academic Journal
- Accession number :
- 16396287