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Iridoid glucosides from the aerial parts of Globularia alypum L. (Globulariaceae).
- Source :
-
Chemical & pharmaceutical bulletin [Chem Pharm Bull (Tokyo)] 2006 Jan; Vol. 54 (1), pp. 85-8. - Publication Year :
- 2006
-
Abstract
- From the hydromethanolic extract of the aerial parts of Globularia alypum grown in Morocco, a new chlorinated iridoid glucoside, globularioside has been isolated beside 5 known iridoid glycosides, globularin, globularicisin, globularidin, globularinin and globularimin. This is the first report of a chlorinated iridoid in G. alypum and in the Globulareaceae. Unlike all other known 7-chlorinated iridoid glucosides where the chlorine atom exhibits an alpha configuration, globularioside incorporate the chlorine atom as a 7beta substituent. The structures of the isolated compounds were established on the basis of ESI-MS, MS-MS, 1D and 2D NMR spectral analysis.
- Subjects :
- Antioxidants chemistry
Antioxidants isolation & purification
Antioxidants pharmacology
Biphenyl Compounds
Carbohydrate Sequence
Chromatography, Liquid
Free Radicals chemistry
Glucosides isolation & purification
Glucosides pharmacology
Iridoids isolation & purification
Iridoids pharmacology
Magnetic Resonance Spectroscopy
Mass Spectrometry
Molecular Sequence Data
Picrates chemistry
Plant Extracts chemistry
Plant Extracts pharmacology
Spectrometry, Mass, Electrospray Ionization
Spectrophotometry, Ultraviolet
Spectroscopy, Fourier Transform Infrared
Glucosides chemistry
Iridoids chemistry
Scrophulariaceae chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 0009-2363
- Volume :
- 54
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Chemical & pharmaceutical bulletin
- Publication Type :
- Academic Journal
- Accession number :
- 16394555
- Full Text :
- https://doi.org/10.1248/cpb.54.85