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Long-term mortality in patients with pauses in ventricular electrical activity.
- Source :
-
Pacing and clinical electrophysiology : PACE [Pacing Clin Electrophysiol] 2005 Nov; Vol. 28 (11), pp. 1203-7. - Publication Year :
- 2005
-
Abstract
- Background: The long-term significance of ventricular pauses of > or =3.0 seconds observed on Holter monitor is unclear, as previously conducted retrospective studies have been poorly controlled. We compared the prognosis of patients with pauses > or =3.0 seconds on Holter monitor with a well-matched control group without such pauses.<br />Methods: Scanning the Holter database at Ochsner Clinic (n = 11,730; January 1998 to June 2003) for pauses > or =3.0 seconds identified 70 patients (pause group). Of those, 29 (37.1%) received a permanent pacemaker (PPM group) and 41 (62.9%) did not (No-PPM group). For each No-PPM patient, two patients without pauses (<2.0 seconds) exactly matched for age, sex, ejection fraction (EF), rhythm, and duration of follow-up were randomly chosen from the Holter database (control group, n = 82) and survival of the two groups was compared.<br />Results: Mean age was 72.5 +/- 15.0 years, mean EF was 52.2 +/- 12.7%, and 68.3% were men. Mean follow-up was 2.2 years (0.5-4.5 years). There was no difference in survival between the No-PPM and the control groups (82.9% vs 84.1%, P = NS). Compared with the PPM group, pauses in the No-PPM group were more commonly asymptomatic, nocturnal, and due to sinus pauses or atrial fibrillation (AF) with slow ventricular response.<br />Conclusions: Pauses in ventricular electrical activity > or =3 seconds on Holter monitor due to sinus pauses or AF with slow ventricular response are not predictive of heightened mortality.
- Subjects :
- Aged
Arrhythmias, Cardiac prevention & control
Cardiac Pacing, Artificial statistics & numerical data
Comorbidity
Female
Heart Rate
Humans
Longitudinal Studies
Louisiana epidemiology
Male
Prevalence
Retrospective Studies
Risk Factors
Survival Analysis
Ventricular Dysfunction, Left prevention & control
Arrhythmias, Cardiac diagnosis
Arrhythmias, Cardiac mortality
Electrocardiography, Ambulatory statistics & numerical data
Risk Assessment methods
Survival Rate
Ventricular Dysfunction, Left diagnosis
Ventricular Dysfunction, Left mortality
Subjects
Details
- Language :
- English
- ISSN :
- 0147-8389
- Volume :
- 28
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Pacing and clinical electrophysiology : PACE
- Publication Type :
- Academic Journal
- Accession number :
- 16359287
- Full Text :
- https://doi.org/10.1111/j.1540-8159.2005.50189.x