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Effects of alpha-tocopherol and related compounds on reactions involving various organic radicals.

Authors :
Povalishev VN
Polozov GI
Shadyro OI
Source :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2006 Mar 01; Vol. 16 (5), pp. 1236-9. Date of Electronic Publication: 2005 Dec 15.
Publication Year :
2006

Abstract

Effects of alpha-tocopherol, PMC, and a number of the respective sulfur-containing analogues on reactions involving various organic radicals were studied. The test compounds were found to interact with alkyl radicals more effectively than with peroxyl radicals. The presence of a sulfur atom in structures of the respective analogues did not produce significant effects on reactivity. Derivatives of 5-hydroxy-1,3-benzoxathiol-2-one and 6-hydroxy-1,4-benzoxathiin-2(3H)-one displayed a high reactivity toward alpha-hydroxyalkyl radicals.

Details

Language :
English
ISSN :
0960-894X
Volume :
16
Issue :
5
Database :
MEDLINE
Journal :
Bioorganic & medicinal chemistry letters
Publication Type :
Academic Journal
Accession number :
16343902
Full Text :
https://doi.org/10.1016/j.bmcl.2005.11.078