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[The genetics of hypogonadotropic hypogonadism in the male].
- Source :
-
MMW Fortschritte der Medizin [MMW Fortschr Med] 2005 Nov 10; Vol. 147 (45), pp. 32-4, 36. - Publication Year :
- 2005
-
Abstract
- Underlying causes of hypogonadotropic hypogonadism are acquired or congenital disorders of the hypothalamus or pituitary (e.g. pituitary adenoma, craniopharyngioma, prior radiotherapy, trauma, severe general diseases, extreme stress, genetic mutations). In addition to a comprehensive history and physical examination, the diagnostic work-up includes measurement of testosterone, LH and FSH, with the aim of differentiating between primary and secondary hypogonadism. Where indicated, investigation of pituitary function, the use of imaging procedures, possibly an olfactory test, a GnRH stimulation test or genetic analyses may be added. Depending upon the indication, treatment is effected with testosterone, GnRH or gonadotropines.
- Subjects :
- Adolescent
Adult
Age Factors
Female
Gonadotropin-Releasing Hormone administration & dosage
Gonadotropin-Releasing Hormone therapeutic use
Gonadotropins administration & dosage
Gonadotropins therapeutic use
Humans
Hypogonadism classification
Hypogonadism diagnosis
Hypogonadism drug therapy
Hypogonadism physiopathology
Leptin genetics
Male
Mutation
Olfaction Disorders diagnosis
Olfaction Disorders etiology
Pregnancy
Puberty, Delayed diagnosis
Receptors, Cell Surface genetics
Receptors, Leptin
Spermatogenesis
Testosterone administration & dosage
Testosterone therapeutic use
Time Factors
Hypogonadism genetics
Infertility, Male genetics
Kallmann Syndrome diagnosis
Kallmann Syndrome genetics
Prader-Willi Syndrome diagnosis
Prader-Willi Syndrome genetics
Subjects
Details
- Language :
- German
- ISSN :
- 1438-3276
- Volume :
- 147
- Issue :
- 45
- Database :
- MEDLINE
- Journal :
- MMW Fortschritte der Medizin
- Publication Type :
- Academic Journal
- Accession number :
- 16320650