Back to Search
Start Over
IBX-mediated alpha-hydroxylation of alpha-alkynyl carbonyl systems. A convenient method for the synthesis of tertiary alcohols.
- Source :
-
The Journal of organic chemistry [J Org Chem] 2005 Nov 25; Vol. 70 (24), pp. 10210-2. - Publication Year :
- 2005
-
Abstract
- [reaction: see text] IBX (o-iodoxybenzoic acid) is an excellent reagent for the alpha-hydroxylation of alpha-alkynyl carbonyl compounds without giving dehydrogenation products. The convenient procedure proves to be useful for the construction of a variety of tertiary alcohols (55-91%) under mildly acidic conditions.
Details
- Language :
- English
- ISSN :
- 0022-3263
- Volume :
- 70
- Issue :
- 24
- Database :
- MEDLINE
- Journal :
- The Journal of organic chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 16292876
- Full Text :
- https://doi.org/10.1021/jo051898j