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Bioactive constituents from roots of Bursera tonkinensis.
- Source :
-
Phytochemistry [Phytochemistry] 2005 Dec; Vol. 66 (23), pp. 2745-51. Date of Electronic Publication: 2005 Nov 09. - Publication Year :
- 2005
-
Abstract
- Bioassay directed-fractionation led to isolation of 12 compounds from the roots of Bursera tonkinensis Guillaum (Burseraceae), including burselignan, bursephenylpropane, and burseneolignan. Of the 12 compounds, only 4'-demethyldesoxypodophyllotoxin exhibited significant cytotoxic activities against KB, Col2 and LNCaP cell lines.
- Subjects :
- Drug Screening Assays, Antitumor
Humans
Lignans chemistry
Lignans isolation & purification
Magnetic Resonance Spectroscopy
Male
Molecular Structure
Podophyllotoxin analogs & derivatives
Podophyllotoxin chemistry
Podophyllotoxin pharmacology
Tumor Cells, Cultured
Antineoplastic Agents, Phytogenic chemistry
Antineoplastic Agents, Phytogenic pharmacology
Bursera chemistry
Plant Roots chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 0031-9422
- Volume :
- 66
- Issue :
- 23
- Database :
- MEDLINE
- Journal :
- Phytochemistry
- Publication Type :
- Academic Journal
- Accession number :
- 16289147
- Full Text :
- https://doi.org/10.1016/j.phytochem.2005.09.025