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Synthesis of a 2,3';6',3''-terpyridine scaffold as an alpha-helix mimetic.

Authors :
Davis JM
Truong A
Hamilton AD
Source :
Organic letters [Org Lett] 2005 Nov 24; Vol. 7 (24), pp. 5405-8.
Publication Year :
2005

Abstract

[reaction: see text] A terpyridine scaffold has been designed as an alpha-helix mimetic. A facile synthesis of the ortho-functionalized 2,3'-oligopyridine has been accomplished using sequential Bohlmann-Rahtz heteroannulation reactions.

Subjects

Subjects :
Catalysis
Molecular Conformation
Molecular Mimicry
Molecular Structure
Palladium chemistry
Pyridines chemical synthesis
Pyridines chemistry

Details

Language :
English
ISSN :
1523-7060
Volume :
7
Issue :
24
Database :
MEDLINE
Journal :
Organic letters
Publication Type :
Academic Journal
Accession number :
16288517
Full Text :
https://doi.org/10.1021/ol0521228
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