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Looking glass inhibitors: efficient synthesis and biological evaluation of D-deoxyfuconojirimycin.
- Source :
-
Carbohydrate research [Carbohydr Res] 2005 Dec 30; Vol. 340 (18), pp. 2713-8. Date of Electronic Publication: 2005 Nov 04. - Publication Year :
- 2005
-
Abstract
- 1,6-Dideoxygalactostatin, the mirror image of 1-deoxy-L-fuconojirimycin, was efficiently prepared from 2,3-O-isopropylidene-L-lyxonolactone in four steps and evaluated as a glycosidase inhibitor.
- Subjects :
- 1-Deoxynojirimycin analogs & derivatives
Humans
Imino Pyranoses chemical synthesis
Imino Pyranoses chemistry
Imino Pyranoses pharmacology
Molecular Conformation
Stereoisomerism
Structure-Activity Relationship
Sugar Alcohols chemistry
Glycoside Hydrolases antagonists & inhibitors
Sugar Alcohols chemical synthesis
Sugar Alcohols pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 0008-6215
- Volume :
- 340
- Issue :
- 18
- Database :
- MEDLINE
- Journal :
- Carbohydrate research
- Publication Type :
- Academic Journal
- Accession number :
- 16274755
- Full Text :
- https://doi.org/10.1016/j.carres.2005.10.002