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Novel phenylamino acetamide derivatives as potent and selective kappa opioid receptor agonists.

Authors :
Chu GH
Gu M
Cassel JA
Belanger S
Stabley GJ
DeHaven RN
Conway-James N
Koblish M
Little PJ
DeHaven-Hudkins DL
Dolle RE
Source :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2006 Feb; Vol. 16 (3), pp. 645-8. Date of Electronic Publication: 2005 Nov 02.
Publication Year :
2006

Abstract

A novel series of phenylamino acetamide derivatives was synthesized. These amides were shown to be potent and selective kappa opioid receptor agonists.

Details

Language :
English
ISSN :
0960-894X
Volume :
16
Issue :
3
Database :
MEDLINE
Journal :
Bioorganic & medicinal chemistry letters
Publication Type :
Academic Journal
Accession number :
16263278
Full Text :
https://doi.org/10.1016/j.bmcl.2005.10.034