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The kinome is not enough.

Authors :
Toogood PL
Source :
Chemistry & biology [Chem Biol] 2005 Oct; Vol. 12 (10), pp. 1057-8.
Publication Year :
2005

Abstract

Mechanism of action studies are essential to link observable effects on cells with molecular targets of small molecules. Caligiuri and coworkers describe how yeast three-hybrid screening identified kinases that might mediate an intriguing tumor cell-specific antiproliferative effect.

Details

Language :
English
ISSN :
1074-5521
Volume :
12
Issue :
10
Database :
MEDLINE
Journal :
Chemistry & biology
Publication Type :
Academic Journal
Accession number :
16242646
Full Text :
https://doi.org/10.1016/j.chembiol.2005.09.011