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In utero stem cell therapy.

Authors :
Diukman R
Golbus MS
Source :
The Journal of reproductive medicine [J Reprod Med] 1992 Jun; Vol. 37 (6), pp. 515-20.
Publication Year :
1992

Abstract

In utero stem cell transplantation offers the potential for treating a number of genetic disorders. The combination of fetal immunotolerance and fetal marrow space makes the fetus an excellent transplant recipient. Experiments on the mouse, sheep and rhesus monkey have indicated that in utero transplantation is feasible. Human trials are currently beginning.

Subjects

Subjects :
Animals
Bone Marrow Transplantation immunology
Bone Marrow Transplantation standards
Clinical Trials as Topic
Disease Models, Animal
Fetal Diseases immunology
Genetic Diseases, Inborn immunology
Humans
Immune Tolerance immunology
Macaca mulatta
Mice
Sheep
Tissue Donors
Treatment Outcome
Bone Marrow Transplantation methods
Erythroid Precursor Cells transplantation
Fetal Diseases therapy
Genetic Diseases, Inborn therapy

Details

Language :
English
ISSN :
0024-7758
Volume :
37
Issue :
6
Database :
MEDLINE
Journal :
The Journal of reproductive medicine
Publication Type :
Academic Journal
Accession number :
1619604

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Authors Abstract Subjects Details