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Bats are natural reservoirs of SARS-like coronaviruses.
- Source :
-
Science (New York, N.Y.) [Science] 2005 Oct 28; Vol. 310 (5748), pp. 676-9. Date of Electronic Publication: 2005 Sep 29. - Publication Year :
- 2005
-
Abstract
- Severe acute respiratory syndrome (SARS) emerged in 2002 to 2003 in southern China. The origin of its etiological agent, the SARS coronavirus (SARS-CoV), remains elusive. Here we report that species of bats are a natural host of coronaviruses closely related to those responsible for the SARS outbreak. These viruses, termed SARS-like coronaviruses (SL-CoVs), display greater genetic variation than SARS-CoV isolated from humans or from civets. The human and civet isolates of SARS-CoV nestle phylogenetically within the spectrum of SL-CoVs, indicating that the virus responsible for the SARS outbreak was a member of this coronavirus group.
- Subjects :
- Amino Acid Sequence
Animals
China epidemiology
Chlorocebus aethiops
Communicable Diseases, Emerging
Disease Outbreaks
Genetic Variation
Genome, Viral
Henipavirus classification
Humans
Molecular Sequence Data
Mutation
Phylogeny
Polymerase Chain Reaction
Sequence Analysis, DNA
Severe Acute Respiratory Syndrome epidemiology
Severe Acute Respiratory Syndrome transmission
Severe Acute Respiratory Syndrome virology
Vero Cells
Viverridae virology
Chiroptera virology
Coronavirus classification
Disease Reservoirs
Severe acute respiratory syndrome-related coronavirus classification
Subjects
Details
- Language :
- English
- ISSN :
- 1095-9203
- Volume :
- 310
- Issue :
- 5748
- Database :
- MEDLINE
- Journal :
- Science (New York, N.Y.)
- Publication Type :
- Academic Journal
- Accession number :
- 16195424
- Full Text :
- https://doi.org/10.1126/science.1118391