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Bats are natural reservoirs of SARS-like coronaviruses.

Authors :
Li W
Shi Z
Yu M
Ren W
Smith C
Epstein JH
Wang H
Crameri G
Hu Z
Zhang H
Zhang J
McEachern J
Field H
Daszak P
Eaton BT
Zhang S
Wang LF
Source :
Science (New York, N.Y.) [Science] 2005 Oct 28; Vol. 310 (5748), pp. 676-9. Date of Electronic Publication: 2005 Sep 29.
Publication Year :
2005

Abstract

Severe acute respiratory syndrome (SARS) emerged in 2002 to 2003 in southern China. The origin of its etiological agent, the SARS coronavirus (SARS-CoV), remains elusive. Here we report that species of bats are a natural host of coronaviruses closely related to those responsible for the SARS outbreak. These viruses, termed SARS-like coronaviruses (SL-CoVs), display greater genetic variation than SARS-CoV isolated from humans or from civets. The human and civet isolates of SARS-CoV nestle phylogenetically within the spectrum of SL-CoVs, indicating that the virus responsible for the SARS outbreak was a member of this coronavirus group.

Details

Language :
English
ISSN :
1095-9203
Volume :
310
Issue :
5748
Database :
MEDLINE
Journal :
Science (New York, N.Y.)
Publication Type :
Academic Journal
Accession number :
16195424
Full Text :
https://doi.org/10.1126/science.1118391