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The BCR signalosome: where cell fate is decided.

Authors :
Ulivieri C
Baldari CT
Source :
Journal of biological regulators and homeostatic agents [J Biol Regul Homeost Agents] 2005 Jan-Jun; Vol. 19 (1-2), pp. 1-16.
Publication Year :
2005

Abstract

B cell antigen receptor (BCR) engagement results in the assembly of a multimolecular complex at the cytosolic side of the plasma membrane, known as signalosome. Here we briefly review the current knowledge on the molecules which participate in the BCR signalosome and on the response modulators which control the final signal output by enhancing or dampening BCR signaling.

Details

Language :
English
ISSN :
0393-974X
Volume :
19
Issue :
1-2
Database :
MEDLINE
Journal :
Journal of biological regulators and homeostatic agents
Publication Type :
Academic Journal
Accession number :
16178270