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Cardiorespiratory fitness, all-cause mortality, and risk of cardiovascular disease in Trinidadian men--the St James survey.
- Source :
-
International journal of epidemiology [Int J Epidemiol] 2005 Dec; Vol. 34 (6), pp. 1387-94. Date of Electronic Publication: 2005 Sep 16. - Publication Year :
- 2005
-
Abstract
- Background: This study examined whether cardiorespiratory fitness is a risk factor for cardiovascular disease, myocardial infarction, and all-cause mortality in a low- to middle-income Trinidadian community of African, South Asian Indian, and European origin. Those of Indian descent have a distinctively high rate of myocardial infarction.<br />Methods: The St James Study is a prospective total community survey located in Port-of-Spain, Trinidad, West Indies. A random sample of 626 men aged 35-69 years, without angina of effort, previous myocardial infarction, partial or complete atrio-ventricular conduction defect, complete heart block, or exercise-induced asthma, was used for the assessment of cardiorespiratory fitness by cycle ergometry. Surveillance for morbidity and mortality was maintained for an average of 7.3 years.<br />Results: When the subjects were grouped into those with an age- and fat-free mass-adjusted peak oxygen uptake above and below the mean of 60.4 mmol/min (1.34 l/min), the hazard ratios (below/above) (95% confidence interval) for all-cause mortality, cardiovascular disease incidence, and incidence of myocardial infarction, after allowance for conventional cardiovascular risk factors, were 2.08 (1.23-3.52), 2.13 (1.22-3.69), and 2.36 (0.84-6.67), respectively. For those unable to achieve a level of work requiring an oxygen uptake of 67 mmol/min (1.5 l/min) during progressive exercise, the respective hazard ratios were 3.49 (1.57-7.76), 2.29 (1.21-4.33), and 5.45 (1.22-24.34). Indian ethnicity remained a predictor of myocardial infarction after allowance for cardiorespiratory performance.<br />Conclusion: Low cardiorespiratory fitness is a risk factor for cardiovascular disease morbidity and mortality in the low- to middle-income developing community of Trinidad.
- Subjects :
- Adult
Aged
Anthropometry
Black People statistics & numerical data
Blood Pressure
Cardiovascular Diseases etiology
Cardiovascular Diseases physiopathology
Diabetic Angiopathies ethnology
Diabetic Angiopathies physiopathology
Electrocardiography
Exercise Test methods
Health Surveys
Humans
India ethnology
Male
Middle Aged
Myocardial Infarction ethnology
Myocardial Infarction etiology
Myocardial Infarction physiopathology
Oxygen Consumption
Risk Factors
Trinidad and Tobago epidemiology
White People statistics & numerical data
Cardiovascular Diseases ethnology
Cause of Death
Physical Fitness
Subjects
Details
- Language :
- English
- ISSN :
- 0300-5771
- Volume :
- 34
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- International journal of epidemiology
- Publication Type :
- Academic Journal
- Accession number :
- 16169888
- Full Text :
- https://doi.org/10.1093/ije/dyi193