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Clinical features of depressed patients with or without a family history of alcoholism.

Authors :
Sher L
Oquendo MA
Conason AH
Brent DA
Grunebaum MF
Zalsman G
Burke AK
Mann JJ
Source :
Acta psychiatrica Scandinavica [Acta Psychiatr Scand] 2005 Oct; Vol. 112 (4), pp. 266-71.
Publication Year :
2005

Abstract

Objective: To compare clinical features of depressed subjects without alcoholism but with a family history of alcoholism to a depressed group without alcoholism and without a family history of alcoholism.<br />Method: Clinical and demographic data of 209 depressed subjects without a history of alcoholism in first-degree relatives and 73 depressed individuals with a history of alcoholism in first-degree relatives were compared. Subjects with a personal history of alcoholism were excluded.<br />Results: Depressed subjects with a family history of alcoholism have a significantly higher prevalence of reported childhood physical and sexual abuse and post-traumatic stress disorder (PTSD), make more suicide attempts, and have greater intent to die at the time of their most lethal suicide attempt, compared to depressed subjects without a family history of alcoholism.<br />Conclusion: Depressed patients with a family history of alcoholism are at greater risk for suicidal behavior and PTSD and may require more careful management.

Details

Language :
English
ISSN :
0001-690X
Volume :
112
Issue :
4
Database :
MEDLINE
Journal :
Acta psychiatrica Scandinavica
Publication Type :
Academic Journal
Accession number :
16156833
Full Text :
https://doi.org/10.1111/j.1600-0447.2005.00591.x