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Meiotic delay of mouse spermatocytes carrying x-ray-induced translocations.
- Source :
-
Cytogenetics and cell genetics [Cytogenet Cell Genet] 1992; Vol. 60 (2), pp. 146-9. - Publication Year :
- 1992
-
Abstract
- The kinetics of spermatocyte progression through meiotic prophase in cells with or without induced translocations were studied in mice that had been exposed to x-rays. Pulse-labeling experiments using 3H-thymidine, followed by autoradiographic analysis, indicated that at higher x-ray doses (6 and 7 Gy), translocation-carrying cells tend to spend more time in meiotic prophase than do normal cells. At 2 Gy, no such delay seemed to be present. The observed delay may explain the reduction in transmission of translocations to the next generation reported by others.
Details
- Language :
- English
- ISSN :
- 0301-0171
- Volume :
- 60
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Cytogenetics and cell genetics
- Publication Type :
- Academic Journal
- Accession number :
- 1611914
- Full Text :
- https://doi.org/10.1159/000133326