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Dynamic range and reproducibility of hepatitis B virus (HBV) DNA detection and quantification by Cobas Taqman HBV, a real-time semiautomated assay.

Authors :
Lindh M
Hannoun C
Source :
Journal of clinical microbiology [J Clin Microbiol] 2005 Aug; Vol. 43 (8), pp. 4251-4.
Publication Year :
2005

Abstract

The Cobas Taqman assay for hepatitis B virus (HBV) DNA showed linear detection over 7 logs for genotypes A to D. The coefficient of variation was 1.2% at > or =1,000 IU/ml and 22.0% at 10 IU/ml. In 97 clinical samples, the log HBV DNA/ml differed by 0.11 between Cobas Amplicor and Cobas Taqman (r2 = 0.97).

Details

Language :
English
ISSN :
0095-1137
Volume :
43
Issue :
8
Database :
MEDLINE
Journal :
Journal of clinical microbiology
Publication Type :
Academic Journal
Accession number :
16081992
Full Text :
https://doi.org/10.1128/JCM.43.8.4251-4254.2005