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Sterically-controlled regioselective para-substitutions of aniline.
- Source :
-
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2005 Aug 14 (30), pp. 3835-7. Date of Electronic Publication: 2005 Jun 24. - Publication Year :
- 2005
-
Abstract
- Introduction of sterically demanding 1-isopropyl-2-methylpropyl or triisopropylsilyl groups at the nitrogen of aniline allows high-yielding regioselective para-substitution to be achieved using a lithiation/substitution sequence.
Details
- Language :
- English
- ISSN :
- 1359-7345
- Issue :
- 30
- Database :
- MEDLINE
- Journal :
- Chemical communications (Cambridge, England)
- Publication Type :
- Academic Journal
- Accession number :
- 16041433
- Full Text :
- https://doi.org/10.1039/b506824j