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Cognitive performance of patients with mesial temporal lobe epilepsy and incidental calcified neurocysticercosis.
- Source :
-
Journal of neurology, neurosurgery, and psychiatry [J Neurol Neurosurg Psychiatry] 2005 Aug; Vol. 76 (8), pp. 1080-3. - Publication Year :
- 2005
-
Abstract
- Objectives: Although chronic calcified neurocysticercosis (NCC) has been considered a major cause of symptomatic epilepsy in developing countries, it can also be an incidental pathological finding in epileptic patients from endemic regions. The mechanisms of brain plasticity occurring in patients with NCC during and after the inflammatory process related to the parasite infection, death, degeneration, and calcification within the host brain might be an independent factor for cognitive impairment in patients with NCC and epilepsy. In order to assess this possibility cognitive performance of patients with mesial temporal lobe epilepsy related to hippocampal sclerosis (MTLE-HS) with and without NCC was investigated through structured neuropsychological testing.<br />Methods: Cognitive performance of long term MTLE-HS patients with (HS-NCC group, n = 32) and without NCC (HS only, n = 48) was compared. Imbalances between the two groups with respect to clinical, demographic, neuroimaging, and electrophysiological variables were adjusted by linear multiple regression analysis and Bonferroni correction for multiple tests.<br />Results and Conclusions: There were no cognitive performance differences between HS-NCC and HS only patients, leading to the conclusion that chronic calcified NCC per se does not aggravate the cognitive performance of patients with long term MTLE-HS.
- Subjects :
- Demography
Electroencephalography
Epilepsy, Temporal Lobe diagnosis
Female
Headache diagnosis
Headache epidemiology
Headache etiology
Humans
Magnetic Resonance Angiography
Magnetic Resonance Imaging
Male
Neurocysticercosis cerebrospinal fluid
Neuropsychological Tests
Prospective Studies
Severity of Illness Index
Sinus Thrombosis, Intracranial epidemiology
Sinus Thrombosis, Intracranial etiology
Brain Diseases parasitology
Brain Diseases pathology
Calcinosis complications
Calcinosis pathology
Cognition Disorders diagnosis
Cognition Disorders etiology
Epilepsy, Temporal Lobe etiology
Neurocysticercosis complications
Neurocysticercosis pathology
Subjects
Details
- Language :
- English
- ISSN :
- 0022-3050
- Volume :
- 76
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Journal of neurology, neurosurgery, and psychiatry
- Publication Type :
- Academic Journal
- Accession number :
- 16024883
- Full Text :
- https://doi.org/10.1136/jnnp.2004.048934