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Effect of nicotine replacement therapy on post-cessation weight gain and nutrient intake: a randomized controlled trial of postmenopausal female smokers.
- Source :
-
Addictive behaviors [Addict Behav] 2005 Aug; Vol. 30 (7), pp. 1273-80. - Publication Year :
- 2005
-
Abstract
- This study of 94 postmenopausal female smokers evaluated the effect of nicotine replacement therapy (NRT) and hormone therapy (HT) on change in weight, energy intake, and physical activity during 2 weeks of smoking abstinence. Women, stratified by current use of HT, were randomized to nicotine or placebo patch. After 2 weeks of abstinence, women on nicotine patch had significantly larger increases in total caloric and fat intake than women on placebo patch and a trend toward larger increases in carbohydrates (total and sweet). Conversely, the nicotine group had less weight gain, 0.47 kg, than the placebo group, 1.02 kg (F=10.31, p=0.002). No effects were observed for hormone therapy. It appears that in short-term smoking abstinence, postmenopausal women on NRT gain less weight than do women on placebo, in spite of consuming more calories. This may be beneficial in the critical first 1-2 weeks of tobacco cessation, especially in light of postmenopausal weight gain.
- Subjects :
- Adult
Aged
Analysis of Variance
Dietary Carbohydrates administration & dosage
Energy Intake drug effects
Estrogen Replacement Therapy
Female
Humans
Middle Aged
Motor Activity drug effects
Nicotine therapeutic use
Tobacco Use Disorder drug therapy
Tobacco Use Disorder physiopathology
Feeding Behavior drug effects
Nicotine pharmacology
Postmenopause physiology
Smoking Cessation methods
Weight Gain drug effects
Subjects
Details
- Language :
- English
- ISSN :
- 0306-4603
- Volume :
- 30
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Addictive behaviors
- Publication Type :
- Academic Journal
- Accession number :
- 16022925
- Full Text :
- https://doi.org/10.1016/j.addbeh.2005.01.003