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How do DCs interact with intestinal antigens?
- Source :
-
Trends in immunology [Trends Immunol] 2005 Jul; Vol. 26 (7), pp. 349-52. - Publication Year :
- 2005
-
Abstract
- Recent evidence demonstrates that dendritic cells (DCs) can insert dendrites between the epithelial cells that form the barrier protecting the body from the gut contents. Although first observed almost a decade ago, this is a controversial area of DC biology and the physiological importance of this phenomenon is only now being clarified. A recent study by Niess and colleagues shows that this behaviour enables efficient sampling of both invasive and non-invasive bacteria and might enhance the ability of an organism to resist infections by a pathogenic strain of Salmonella.
- Subjects :
- Animals
Antigens administration & dosage
Antigens, Bacterial administration & dosage
Dendritic Cells microbiology
Immune Tolerance
Intestines microbiology
Lymph Nodes immunology
Lymph Nodes microbiology
Salmonella immunology
Salmonella pathogenicity
Dendritic Cells immunology
Intestines immunology
Subjects
Details
- Language :
- English
- ISSN :
- 1471-4906
- Volume :
- 26
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Trends in immunology
- Publication Type :
- Academic Journal
- Accession number :
- 15978521
- Full Text :
- https://doi.org/10.1016/j.it.2005.04.010