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Prolonged acute hepatitis A mimicking autoimmune hepatitis.
- Source :
-
World journal of gastroenterology [World J Gastroenterol] 2005 Jun 28; Vol. 11 (24), pp. 3791-3. - Publication Year :
- 2005
-
Abstract
- Aim: We report a case with a prolonged course of hepatitis A, with alanine aminotransferase (ALT) higher than 500 IU/L for more than 2 mo.<br />Methods: A middle-aged woman had an elevated IgG level of more than 2,000 mg/dL, positive anti-nuclear antibodies (ANA) and anti-smooth muscle antibodies (ASMA), but no evidence of persistent hepatitis A virus (HAV) infection. Liver biopsy findings were compatible with prolonged acute hepatitis, although acute onset of autoimmune hepatitis could not be ruled out.<br />Results: It was assumed that she developed a course of hepatitis similar to autoimmune hepatitis triggered by HAV infection. Ursodeoxycholic acid (UDCA) treatment was initiated and a favorable outcome was obtained.<br />Conclusion: We describe a case of a middle-aged woman who showed a prolonged course of acute hepatitis A mimicking autoimmune hepatitis. Treatment with UDCA proved to be effective.
- Subjects :
- Acute Disease
Antibodies, Antinuclear blood
Cholagogues and Choleretics therapeutic use
Diagnosis, Differential
Female
Hepatitis A drug therapy
Hepatitis A immunology
Hepatitis, Autoimmune immunology
Humans
Middle Aged
Ursodeoxycholic Acid therapeutic use
Hepatitis A diagnosis
Hepatitis, Autoimmune diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1007-9327
- Volume :
- 11
- Issue :
- 24
- Database :
- MEDLINE
- Journal :
- World journal of gastroenterology
- Publication Type :
- Academic Journal
- Accession number :
- 15968741
- Full Text :
- https://doi.org/10.3748/wjg.v11.i24.3791