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[Primary, nonviral, hepatocellular carcinoma in patients with prostate cancer treated by hormone therapy: 2 case reports].
- Source :
-
Nihon Hinyokika Gakkai zasshi. The japanese journal of urology [Nihon Hinyokika Gakkai Zasshi] 2005 May; Vol. 96 (4), pp. 503-6. - Publication Year :
- 2005
-
Abstract
- We studied two cases of primary, hepatocellular carcinoma (HCC) that occurred following hormone therapy (estrogen therapy in one case and total androgen blockade therapy in another) for stage D2 prostate cancer. Prostate cancer is considered to be hormone-dependent, and androgens appear to be important hormonal factors. However, hepatocellular carcinoma has been shown to have both estrogen and androgen receptors, suggesting that this may be dependent on estrogen or androgen. Reported here are two unique cases of hepatocellular carcinoma in patients with prostate cancer; the pathogenesis of HCC in these patients was suspected to be related to diethylstilbestrol (DES) therapy and antiandrogen therapy for their prostate cancer.
- Subjects :
- Aged
Carcinoma, Hepatocellular pathology
Drug Administration Schedule
Humans
Liver Neoplasms pathology
Male
Middle Aged
Neoplasms, Second Primary pathology
Prostatic Neoplasms pathology
Androgen Antagonists therapeutic use
Antineoplastic Agents, Hormonal therapeutic use
Carcinoma, Hepatocellular etiology
Diethylstilbestrol analogs & derivatives
Diethylstilbestrol therapeutic use
Liver Neoplasms etiology
Neoplasms, Second Primary etiology
Prostatic Neoplasms drug therapy
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0021-5287
- Volume :
- 96
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Nihon Hinyokika Gakkai zasshi. The japanese journal of urology
- Publication Type :
- Academic Journal
- Accession number :
- 15948411
- Full Text :
- https://doi.org/10.5980/jpnjurol1989.96.503