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Prognosis of patients with good exercise capacity and mildly abnormal exercise echocardiography results: identification of an at-risk subgroup.

Authors :
McCully RB
Ommen SR
Klarich KW
Burger KN
Mahoney DW
Pellikka PA
Source :
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography [J Am Soc Echocardiogr] 2005 Jun; Vol. 18 (6), pp. 644-8.
Publication Year :
2005

Abstract

Background: Patients with good exercise capacity and mildly abnormal exercise echocardiography results have a favorable overall prognosis.<br />Objective: We sought to define subgroups that might be at higher risk.<br />Methods: We examined outcomes of 868 patients (women, > or = 5 metabolic equivalents; men, > or = 7 metabolic equivalents) with mild rest- or exercise-induced wall-motion abnormalities and evaluated potential predictors of time to cardiac death or nonfatal myocardial infarction (MI).<br />Results: Mean age was 64 +/- 10 years; 477 patients (55%) were men. Mean follow-up was 3.1 +/- 1.5 years; cardiac event rate was 1.2% per person-year. A history of MI was the only significant predictor (risk ratio, 3.9; 95% confidence interval, 1.9-7.8; P = .0001), with 1-, 3-, and 5-year event-free survival of 98.5% +/- 1.1%, 92.6% +/- 2.6%, and 83.3% +/- 5.1%, respectively (event rate, 3.4%).<br />Conclusions: Patients with a history of MI have a higher annual cardiac event rate and may benefit from reevaluation, whereas no history of MI connotes a favorable prognosis.

Details

Language :
English
ISSN :
1097-6795
Volume :
18
Issue :
6
Database :
MEDLINE
Journal :
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
Publication Type :
Academic Journal
Accession number :
15947766
Full Text :
https://doi.org/10.1016/j.echo.2004.10.027