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[Parkinson's disease, progressive lumbar kyphosis and focal paraspinal myositis].

Authors :
Charpentier P
Dauphin A
Stojkovic T
Cotten A
Hurtevent JF
Maurage CA
Thévenon A
Destée A
Defebvre L
Source :
Revue neurologique [Rev Neurol (Paris)] 2005 Apr; Vol. 161 (4), pp. 459-63.
Publication Year :
2005

Abstract

Introduction: The camptocormia (bent spine) is characterized by a severe forward flexion of the thoracolumbar spine which disappears in the supine position. Clinical case. We describe a typical case observed in a parkinsonian patient. The MRI, electromyogram and biopsy of the paraspinal muscles revealed a typical myositis pattern.<br />Discussion: This case, the sixth published to our knowledge, confirms that focal myositis is associated with the camptocormia in Parkinson's disease. Typically it is observed in male subjects, appearing 4 to 6 years after the onset of Parkinson's disease, in fluctuating patients treated by an association of L-Dopa and agonist. It appears quickly and becomes the most important symptom. Antiparkinsonian drugs are useless.<br />Conclusion: This exceptional picture raises original pathophysiological and therapeutic questions. Systematic studies should be performed in order to detail the pathophysiological link between these 3 entities: Parkinson's disease, focal myositis and camptocormia.

Details

Language :
French
ISSN :
0035-3787
Volume :
161
Issue :
4
Database :
MEDLINE
Journal :
Revue neurologique
Publication Type :
Academic Journal
Accession number :
15924083
Full Text :
https://doi.org/10.1016/s0035-3787(05)85077-5