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[Parkinson's disease, progressive lumbar kyphosis and focal paraspinal myositis].
- Source :
-
Revue neurologique [Rev Neurol (Paris)] 2005 Apr; Vol. 161 (4), pp. 459-63. - Publication Year :
- 2005
-
Abstract
- Introduction: The camptocormia (bent spine) is characterized by a severe forward flexion of the thoracolumbar spine which disappears in the supine position. Clinical case. We describe a typical case observed in a parkinsonian patient. The MRI, electromyogram and biopsy of the paraspinal muscles revealed a typical myositis pattern.<br />Discussion: This case, the sixth published to our knowledge, confirms that focal myositis is associated with the camptocormia in Parkinson's disease. Typically it is observed in male subjects, appearing 4 to 6 years after the onset of Parkinson's disease, in fluctuating patients treated by an association of L-Dopa and agonist. It appears quickly and becomes the most important symptom. Antiparkinsonian drugs are useless.<br />Conclusion: This exceptional picture raises original pathophysiological and therapeutic questions. Systematic studies should be performed in order to detail the pathophysiological link between these 3 entities: Parkinson's disease, focal myositis and camptocormia.
Details
- Language :
- French
- ISSN :
- 0035-3787
- Volume :
- 161
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Revue neurologique
- Publication Type :
- Academic Journal
- Accession number :
- 15924083
- Full Text :
- https://doi.org/10.1016/s0035-3787(05)85077-5