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[Ictal alteration of 99mTc ECD SPECT imaging in a patient with secondary paroxysmal kinesigenic dyskinesia caused by hyperglycemia].
- Source :
-
Rinsho shinkeigaku = Clinical neurology [Rinsho Shinkeigaku] 2005 Apr; Vol. 45 (4), pp. 312-6. - Publication Year :
- 2005
-
Abstract
- We described a 61-year-old man with diabetes mellitus who presented with hyperglycemia related paroxysmal kinesigenic dyskinesia (PKD) with sudden development of paroxysmal unilateral involuntary movements (IMs) of his neck and the left extremities. Ictal 99mTc-ethylcysteinate dimer SPECT (ECD-SPECT) revealed a hyperperfusion over the contralateral frontal cortex and a hypoperfusion over the contralateral basal ganglia. Immediate correction of hyperglycemia after admission resulted in a marked improvement of IMs and a return to normal cerebral blood flow on interictal ECD-SPECT imaging. These findings suggest that dysfunction of the indirect pathway through the basal ganglia lead to an imbalance of the cortico-striato-thalamo-cortical circuit and may have contributed to the cause of PKD in this case.
- Subjects :
- Basal Ganglia pathology
Cerebrovascular Circulation
Chorea etiology
Chorea physiopathology
Diabetes Complications complications
Electroencephalography
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Organotechnetium Compounds
Radiopharmaceuticals
Basal Ganglia diagnostic imaging
Chorea diagnostic imaging
Cysteine analogs & derivatives
Hyperglycemia complications
Tomography, Emission-Computed, Single-Photon
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0009-918X
- Volume :
- 45
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Rinsho shinkeigaku = Clinical neurology
- Publication Type :
- Academic Journal
- Accession number :
- 15912801