Back to Search
Start Over
Fusion image of positron emission tomography and computed tomography for the diagnosis of local recurrence of rectal cancer.
- Source :
-
Annals of surgical oncology [Ann Surg Oncol] 2005 Jul; Vol. 12 (7), pp. 561-9. Date of Electronic Publication: 2005 May 09. - Publication Year :
- 2005
-
Abstract
- Background: The aim of this study was to evaluate the clinical and therapeutic value of digital fusion image (FI) of positron emission tomography (PET) using (18)F-fluorodeoxy glucose and computed tomography (CT) in patients who were suspected of having a local recurrence of rectal cancer.<br />Methods: Forty-two patients (32 men and 10 women; mean age, 61.4 years, range, 40-79 years) with a suspicion of local recurrence after curative resection of rectal cancer were prospectively recruited and underwent (18)F-fluorodeoxy glucose-PET and CT. The FI was reconstructed with a commercially available digital software program, T-B Fusion. Wilcoxon signed rank test was used to compare FI with CT alone or PET alone.<br />Results: FI yielded a correct diagnosis in 39 (93%) of 42 patients, whereas CT alone and PET alone did so in 33 (79%) and 37 (88%) patients, respectively. FI had better diagnostic accuracy than CT alone (P = .0138) and PET alone (P = .0156). Overall, FI altered patient management in 11 (26.2%) patients on the basis of additional information, including differentiation of the tumor from the postoperative scar in 6 patients, exact anatomical location in 3 patients, and both in 2 patients.<br />Conclusions: FI has a potential clinical value in the treatment of suspected local recurrence of rectal cancer.
- Subjects :
- Adenocarcinoma surgery
Adult
Aged
Colectomy
Female
Fluorodeoxyglucose F18
Humans
Image Processing, Computer-Assisted
Male
Middle Aged
Radiopharmaceuticals
Rectal Neoplasms surgery
Adenocarcinoma diagnosis
Neoplasm Recurrence, Local diagnosis
Positron-Emission Tomography methods
Rectal Neoplasms diagnosis
Tomography, X-Ray Computed methods
Subjects
Details
- Language :
- English
- ISSN :
- 1068-9265
- Volume :
- 12
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Annals of surgical oncology
- Publication Type :
- Academic Journal
- Accession number :
- 15889211
- Full Text :
- https://doi.org/10.1245/ASO.2005.08.001