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Dual-action penems and carbapenems.
- Source :
-
Journal of medicinal chemistry [J Med Chem] 1992 May 15; Vol. 35 (10), pp. 1828-39. - Publication Year :
- 1992
-
Abstract
- Two new series of dual-action antibacterial agents were synthesized in which penems and carbapenems were linked at the 2'-position to quinolones through either an ester or a carbamate moiety. Potent, broad-spectrum antibacterial activity was observed for both classes of compounds, indicative of a dual-mode of action.
Details
- Language :
- English
- ISSN :
- 0022-2623
- Volume :
- 35
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Journal of medicinal chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 1588561
- Full Text :
- https://doi.org/10.1021/jm00088a019