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A switch in enantiomer preference between mitochondrial F1F0-ATPase chemotypes.
- Source :
-
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2005 Jun 02; Vol. 15 (11), pp. 2749-51. - Publication Year :
- 2005
-
Abstract
- The preferred absolute configuration of two series of F(1)F(0)-ATP synthase inhibitors was determined. Although the configuration of the active enantiomer in each series is different, each series presents the same 'triaryl' pharmacophore to the enzyme binding site.
Details
- Language :
- English
- ISSN :
- 0960-894X
- Volume :
- 15
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Bioorganic & medicinal chemistry letters
- Publication Type :
- Academic Journal
- Accession number :
- 15878269
- Full Text :
- https://doi.org/10.1016/j.bmcl.2005.03.115