Prevalence of the ermB gene in Clostridium difficile strains isolated at a university teaching hospital from 1987 through 1998.

Authors :: Tang-Feldman YJ
Henderson JP
Ackermann G
Feldman SS
Bedley M
Silva J Jr
Cohen SH
Source :: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2005 May 15; Vol. 40 (10), pp. 1537-40. Date of Electronic Publication: 2005 Apr 12.
Publication Year :: 2005
Abstract: We analyzed 226 strains of Clostridium difficile for the presence of erythromycin ribosomal methylase B (ermB) genes. Forty-four strains (19.4%) carried ermB genes and were resistant to erythromycin. Toxin A and toxin B gene sequences were identified in 81.9% of these 44 strains. Strains of C. difficile that carry ermB genes are common etiologic agents of C. difficile-associated diarrhea.

Subjects :: Anti-Bacterial Agents pharmacology
Bacterial Proteins
Bacterial Toxins
Clindamycin pharmacology
Clostridioides difficile classification
Clostridioides difficile drug effects
Diarrhea microbiology
Drug Resistance, Bacterial
Enterotoxins
Erythromycin pharmacology
Genotype
Humans
Phenotype
Time Factors
Clostridioides difficile genetics
Clostridioides difficile isolation & purification
Hospitals, University
Methyltransferases genetics

Language :: English
ISSN :: 1537-6591
Volume :: 40
Issue :: 10
Database :: MEDLINE
Journal :: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Publication Type :: Academic Journal
Accession number :: 15844079
Full Text :: https://doi.org/10.1086/428835

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