An old target revisited: two new privileged skeletons and an unexpected binding mode for HIV-protease inhibitors.

Authors :: Specker E
Böttcher J
Lilie H
Heine A
Schoop A
Müller G
Griebenow N
Klebe G
Source :: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2005 May 13; Vol. 44 (20), pp. 3140-4.
Publication Year :: 2005

Subjects :: Binding Sites
Drug Evaluation, Preclinical
Humans
Hydrogen Bonding
Models, Molecular
Molecular Structure
Structure-Activity Relationship
Drug Design
HIV Protease Inhibitors chemical synthesis
HIV Protease Inhibitors chemistry
Sulfones chemical synthesis
Sulfones chemistry

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