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Case report: hypertension in Cushing's syndrome.

Authors :
Suzuki H
Shibata H
Murakami M
Nakamoto H
Kondo K
Saruta T
Source :
The American journal of the medical sciences [Am J Med Sci] 1992 May; Vol. 303 (5), pp. 329-32.
Publication Year :
1992

Abstract

Pathogenesis of hypertension in Cushing's syndrome has remained controversial. A 56-year-old Japanese man with Cushing's syndrome due to adrenal carcinoma has been followed up for more than 6 years. During the followup period, left adrenalectomy and hemihepatectomy due to metastatic lesion were performed. Blood pressure, serum cortisol, and urinary excretion of 17-OHCS, as well as other routine biochemicals, have been measured periodically. These data revealed that there is a marked correlation between the levels of blood pressure and serum cortisol or urinary excretion of 17-OHCS. This finding suggests that cortisol production by tumor is a determinant factor in hypertension in Cushing's syndrome.

Details

Language :
English
ISSN :
0002-9629
Volume :
303
Issue :
5
Database :
MEDLINE
Journal :
The American journal of the medical sciences
Publication Type :
Academic Journal
Accession number :
1580324
Full Text :
https://doi.org/10.1097/00000441-199205000-00013